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Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic and inflammatory disease. It may progress indefinitely and may not go away completely. Its symptoms may disappear for some time but you may encounter frequent flares. It is also a systemic disease. It can attack other organs in your body such as the skin, blood vessels, lungs, and heart.

It begins with the inflammation that affects the lining of the joints called synovium. It can damage the joints if left untreated. As a result, you end up with chronic pain, loss of function, and eventually, disability.

Rheumatoid arthritis progresses in three stages. The first stage happens when an unknown trigger activates the immune system, which instructs the lymphocytes to send cytokines, their chemical messengers, to the affected area. Lymphocytes are white blood cells that are responsible for immune responses. This reaction causes the swelling of the synovial lining where both ends of the bones meet. This causes pain and stiffness around the joints.

The second stage begins with the rapid division and growth of cells, or pannus. At this stage, the synovium become thicker and you will experience more pain. In the third stage, the inflamed cells release enzymes that attack the bone and the cartilage. As a result, deformity of the bones and loss of mobility develops besides increased pain.

Early diagnosis of this disease can help in fighting rheumatoid arthritis more effectively. Medical reports suggest that aggressive treatment in the early phase may stop the disease from progressing. You have to be aware that all current treatments for this disease primarily focus on reducing the painful condition. If possible, they may prevent it from getting worse.

For more information on rheumatoid arthritis treatment, please click the articles below.

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• Rheumatoid Arthritis Treatments
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